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1.
Eur Arch Otorhinolaryngol ; 280(3): 1131-1145, 2023 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-35965274

RESUMO

PURPOSE: Treatment of Menière's Disease (MD) comprises an array of both non-destructive and destructive treatment options. In patients who are therapy-refractory to non-destructive medical treatment, endolymphatic mastoid shunt surgery (EMSS) is both recommended and debated controversially. The aim of this study was to investigate safety in terms of hearing, vestibular function, complication rate, and efficacy with regards to vertigo control of EMSS in patients with MD according to the current diagnostic criteria of 2015. METHODS: Retrospective analysis of 47 consecutive patients with definite or probable MD with description of demographic parameters, pre- and postoperative MD treatment, pre- and postoperative audiometric (pure tone audiometry) and vestibular (caloric testing) results. The parameters were compared between patients with and without postoperative vertigo control. RESULTS: 31/47 patients (66.0%) had improved vertigo control postoperatively. Postoperative hearing and vestibular preservation were predominantly stable. No significant differences between patients with improved vertigo control and patients with no change or worse vertigo episodes were found. In the treatment refractory group, 4 patients required a revision EMSS and 6 a destructive MD treatment (5 gentamicin intratympanically, 1 labyrinthectomy). No peri- or postsurgical complications were reported. CONCLUSIONS: EMSS was found to be beneficial in two thirds of the patients with definite or probable Morbus Menière and a safe procedure regarding hearing and vestibular preservation with no postoperative complications. Therefore, EMSS should be considered before inducing destructive treatment options, such as intratympanic gentamicin application or labyrinthectomy.


Assuntos
Anastomose Endolinfática , Doença de Meniere , Vestíbulo do Labirinto , Humanos , Doença de Meniere/complicações , Doença de Meniere/cirurgia , Estudos Retrospectivos , Processo Mastoide/cirurgia , Vertigem/etiologia , Anastomose Endolinfática/efeitos adversos , Gentamicinas/uso terapêutico
2.
Rehabilitación (Madr., Ed. impr.) ; 56(3): 215-225, Jul - Sep 2022. tab, graf
Artigo em Espanhol | IBECS | ID: ibc-204912

RESUMO

El tratamiento conservador de los pacientes con linfedema habitualmente comprende la terapia descongestiva compleja con objetivo de reducir el volumen y las prendas de compresión en fase de mantenimiento, realizando un seguimiento en los servicios de Rehabilitación. El tratamiento quirúrgico del linfedema es una opción terapéutica cuyo interés ha aumentado en los últimos años, aunque no existe evidencia actual de que pueda curar el linfedema y siempre se acompaña de tratamiento conservador. La mayoría de los estudios se centran en los resultados según el tipo de cirugía y no existe un protocolo estandarizado sobre el tratamiento conservador antes o después de la cirugía. Con este trabajo se pretende realizar un compendio sobre las cirugías de linfedema más frecuentes y sus indicaciones, centrándose en el tratamiento rehabilitador que implica cada cirugía.(AU)


Conservative treatment of lymphedema usually includes complex decongestive therapy in order to reduce the volume of the lymphedema, and compression garments in the maintenance phase. Follow-up is carried out in the Rehabilitation Services. Surgical treatment of lymphedema is a therapeutic option, the interest of which has increased in recent years, although there is no current evidence that it can cure lymphedema and it is always accompanied by conservative treatment. Most studies focus on results according to the type of surgery and there is no standardized protocol for conservative treatment before or after surgery. The objective of this work is to prepare a compendium about the most frequent lymphedema surgeries and their indications, focusing on the rehabilitation treatment for each surgery.(AU)


Assuntos
Linfedema/reabilitação , Linfedema/cirurgia , Linfedema/terapia , Anastomose Endolinfática , Linfonodos , Lipectomia , Medicina Física e Reabilitação
3.
Am J Otolaryngol ; 42(1): 102817, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-33202330

RESUMO

Meniere's disease is a peripheral audiovestibular disorder characterized by vertigo, hearing loss, tinnitus, and aural fullness. Management of these symptoms includes medical and surgical treatment. Many patients with Meniere's disease can be managed using nonablative therapy, such as intratympanic steroids and endolymphatic shunt surgery, prior to ablative techniques such as intratympanic gentamicin. Recognition of concurrent migraine symptoms may aid in medical therapy and also underscore the importance of preserving vestibular function where possible. The goal of this review is to explain the importance of nonablative therapy options and discuss treatment protocols after medical failure.


Assuntos
Doença de Meniere/terapia , Vestíbulo do Labirinto/fisiologia , Dexametasona/administração & dosagem , Anastomose Endolinfática , Gentamicinas/administração & dosagem , Humanos , Doença de Meniere/fisiopatologia , Tratamentos com Preservação do Órgão/métodos , Falha de Tratamento
4.
Laryngoscope ; 130(10): 2455-2460, 2020 10.
Artigo em Inglês | MEDLINE | ID: mdl-31808957

RESUMO

OBJECTIVE: To report audiovestibular outcomes following endolymphatic shunt surgery (ELS) and intratympanic gentamicin injections (ITG) in patients with Meniere's disease (MD). STUDY DESIGN: Retrospective matched cohort study METHODS: Patients with MD refractory to medical management between 2004 and 2017 were reviewed: 44 patients underwent ELS and had outcomes available, while 27 patients underwent ITG and had outcomes available. Mean follow-up durations for the ELS and ITG groups were 39.1 and 43.3 months, respectively. Twenty-six patients from the ELS group and 24 patients from the ITG group were then included in a pretreatment hearing- and age-matched analysis. Main outcome measures were successful control of vertigo, pure-tone average (PTA; 0.5, 1, 2 and 4 kHz), word recognition score (WRS), and treatment complications. RESULTS: A matched analysis showed vertigo control rates of 73.1% in the ELS group and 66.8% in the ITG group, which were not significantly different (P = .760). The change in PTA following treatment was statistically similar between the ELS group (6.2 dB) and ITG group (4.6 dB) (P = .521), while the change in WRS for the ELS group (+3.9 %) was significantly more favorable than the ITG group (-13.6 %) (P = .046). Chronic post-treatment unsteadiness was reported in 25.0% of the ITG group and was not encountered in the ELS group (P = .009). CONCLUSION: ELS provided successful vertigo control at least as well as ITG with a lower incidence of audiovestibular complications. LEVEL OF EVIDENCE: 4 Laryngoscope, 130:2455-2460, 2020.


Assuntos
Anastomose Endolinfática , Gentamicinas/uso terapêutico , Doença de Meniere/terapia , Inibidores da Síntese de Proteínas/uso terapêutico , Audiometria de Tons Puros , Feminino , Gentamicinas/administração & dosagem , Humanos , Masculino , Pessoa de Meia-Idade , Inibidores da Síntese de Proteínas/administração & dosagem , Estudos Retrospectivos , Membrana Timpânica/efeitos dos fármacos
5.
Eur Arch Otorhinolaryngol ; 276(6): 1617-1624, 2019 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-30929055

RESUMO

PURPOSE: Identification of the endolymphatic sac has failed occasionally. Postoperative complications have also rarely been reported. Given a safer and more reliable surgery, preoperative anatomical assessments are valuable, however, the vestibular aqueduct has seldom been seen with multi-planar reconstruction (MPR) computed tomography (CT) images yet. Our study aimed to determine the significance and utility of volume-rendered (VR) CT images of the surgical field for identifying the vestibular aqueduct, compared with MPR CT images. SUBJECTS AND METHODS: 14 patients with Meniere's disease who underwent endolymphatic sac surgery between 2008 and 2011. Location and size of the vestibular aqueduct were assessed using VR and MPR CT images, independently. RESULTS: Accuracy of identifying the location differed significantly between VR and MPR CT images (rate of total correct evaluations: 100% by VR CT images vs 75% by MPR CT images, p = 0.02). Size was correctly identified in cases with a small endolymphatic sac using VR CT images (rate of total correct evaluations for size of the vestibular aqueduct: 100% by VR CT vs 57% by MPR CT, p = 0.046). VR CT images also demonstrated clearly the relationship between the endolymphatic sac and high jugular bulb. In two cases, the endolymphatic sac was identified by VR images, not by MPR images. CONCLUSION: Accurate information about the location and size of vestibular aqueduct can allow sac surgeons to identify a tiny endolymphatic sac more easily and certainly, and also aids surgical trainees to learn sac surgery safely.


Assuntos
Saco Endolinfático/diagnóstico por imagem , Anastomose Endolinfática , Imageamento Tridimensional/métodos , Doença de Meniere/cirurgia , Tomografia Computadorizada por Raios X/métodos , Adulto , Idoso , Saco Endolinfático/cirurgia , Feminino , Humanos , Masculino , Doença de Meniere/diagnóstico por imagem , Pessoa de Meia-Idade , Estudos Retrospectivos , Resultado do Tratamento
6.
Auris Nasus Larynx ; 45(3): 393-398, 2018 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-28760332

RESUMO

Meniere's disease is an inner ear disease, characterized by recurrent rotatory vertigo, sensorineural hearing loss and tinnitus. There are some with frequent vertigo attacks, progressive hearing loss and persistent annoying tinnitus even through the continuous standard medical treatments. These cases are thought to account for 10%-20% of all cases of Meniere's disease. In this review article, we would like to demonstrate the evidences for surgical treatments according to the previous papers, and consider the next therapeutic strategies including surgical options according to the international guidelines.


Assuntos
Técnicas de Ablação/métodos , Denervação/métodos , Anastomose Endolinfática/métodos , Doença de Meniere/cirurgia , Nervo Vestibular/cirurgia , Saco Endolinfático/cirurgia , Medicina Baseada em Evidências , Gentamicinas/uso terapêutico , Humanos , Injeção Intratimpânica , Inibidores da Síntese de Proteínas/uso terapêutico
7.
Auris Nasus Larynx ; 45(3): 427-432, 2018 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-28774486

RESUMO

OBJECTIVE: To evaluate the histopathologic changes in tympanic membranes (TMs) with ventilation tubes (VTs). METHODS: In this retrospective human temporal bone study our overall study group included 4 subgroups of TMs from deceased donors as follows: 24 with a history of VT insertion for chronic otitis media with effusion (COME-VT); 5 with a history of VT insertion for Meniere's disease (MD-VT); 33 without a history of VT insertion for chronic otitis media with effusion (COME); and 14 without a history of VT insertion for Meniere's disease (MD). We classified the extent of migration of the outer keratinized squamous epithelium onto the inner surface of TM perforations and noted the presence and location of tympanosclerosis, of atrophy, of perforation, and/or of cholesteatoma formation. RESULTS: Tympanosclerosis occurred in 14/24 TMs in the COME-VT subgroup; 2/5, MD-VT; 7/33, COME; and 0/14, MD. The VT insertion site was mostly in the anteroinferior (63%) quadrant of the TM; tympanosclerosis occurred more frequently in the posteroinferior (42%) and posterosuperior (33%) quadrants. We found no significant correlation between the location of tympanosclerosis and the VT insertion site (P>0.05). Atrophy occurred in 7/24 TMs in the COME-VT subgroup; 3/5, MD-VT; 8/33, COME; and 2/14, MD. We found no significant correlation between the location of atrophy and the VT insertion site; however, atrophy was located mostly in the anteroinferior quadrant (one of the most common VT insertion sites) of the TM. Regarding the ingrowth of keratinized epithelium, the mucocutanous junction was detected at any point at the inner surface of the TM in 50% of the specimens. We observed intratympanic cholesteatoma formation in 2/24 TMs in the COME-VT subgroup. CONCLUSION: TM changes due to VT insertion are more common than previously realized. Meticulous otomicroscopic evaluation of the TM is necessary during tympanomastoidectomies in order to prevent the intratympanic inclusion pearls and squamous epithelial ingrowth to prevent any further cholesteatoma formation.


Assuntos
Colesteatoma da Orelha Média/patologia , Células Epiteliais/patologia , Doença de Meniere/cirurgia , Ventilação da Orelha Média , Miringoesclerose/patologia , Otite Média com Derrame/cirurgia , Perfuração da Membrana Timpânica/patologia , Membrana Timpânica/patologia , Adolescente , Adulto , Idoso , Atrofia , Cadáver , Criança , Pré-Escolar , Doença Crônica , Anastomose Endolinfática , Feminino , Humanos , Lactente , Masculino , Doença de Meniere/patologia , Pessoa de Meia-Idade , Otite Média com Derrame/patologia , Estudos Retrospectivos , Osso Temporal/patologia , Adulto Jovem
8.
Am J Otolaryngol ; 38(3): 285-290, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-28214024

RESUMO

OBJECTIVES: To evaluate the long-term efficacy of endolymphatic sac shunt techniques with and without local steroid administration. STUDY DESIGN: Retrospective case series and patient survey. SETTING: Tertiary university hospital. PATIENTS: Meniere's disease (MD) patients that failed medical therapy and subsequently underwent an endolymphatic sac shunt procedure. All patients had definitive or probable MD and at least 18-months of follow-up. INTERVENTIONS: Three variations on endolymphatic sac decompression with shunt placement were performed: Group A received no local steroids, Group B received intratympanic dexamethasone prior to incision, and Group C received dexamethasone via both intratympanic injection and direct endolymphatic sac instillation. MAIN OUTCOME MEASURE(S): Vertigo control, hearing results, and survey responses. RESULTS: Between 2002 and 2013, 124 patients with MD underwent endolymphatic sac decompression with shunt placement. 53 patients met inclusion criteria. Groups A, B, and C had 6 patients, 20 patients, and 27 patients, respectively. Mean follow-up was 56months. Vertigo control improved in 66%, 83%, and 93% of Groups A, B, and C. Functional level improved for Group B (-2.0) and Group C (-2.2) but was unchanged in Group A. Pure-tone average and speech discrimination scores changed by +22dB and -30%, +6dB and -13%, and +6dB and -5% in Groups A, B, and C. The long-term hearing results were significantly better with steroids (Groups B and C) according to the AAO-HNS 1995 criteria but did not meet significance on non-parametric testing. CONCLUSIONS: Endolymphatic sac shunt procedures may benefit from steroid instillation at the time of shunt placement.


Assuntos
Dexametasona/administração & dosagem , Saco Endolinfático/cirurgia , Anastomose Endolinfática/métodos , Audição/fisiologia , Doença de Meniere/terapia , Procedimentos Cirúrgicos Otológicos/métodos , Adulto , Idoso , Audiometria de Tons Puros , Feminino , Seguimentos , Glucocorticoides/administração & dosagem , Humanos , Injeção Intratimpânica , Instilação de Medicamentos , Masculino , Doença de Meniere/diagnóstico , Doença de Meniere/fisiopatologia , Pessoa de Meia-Idade , Estudos Retrospectivos , Fatores de Tempo , Resultado do Tratamento , Adulto Jovem
9.
Otol Neurotol ; 37(8): 1128-30, 2016 09.
Artigo em Inglês | MEDLINE | ID: mdl-27525624

RESUMO

OBJECTIVE: Endolymphatic hydrops has been well described in patients with Ménière's syndrome; however, causation has not been established. Decompression of the endolymphatic sac has been proposed as a means to relieve hydrops and improve vertigo symptoms, but the efficacy of the surgery is debated. Until recently, there have been few objective measures of efficacy other than patients' subjective symptoms. Recent archival human temporal bone studies have shown that patients continue to have hydrops after shunt surgery. We propose using high-resolution magnetic resonance imaging (MRI) to determine the efficacy of endolymphatic shunt surgery (ELS) in patients who continue to experience vertigo. PATIENTS: Four patients presented with continued vertigo after ELS. INTERVENTIONS: Magnetic resonance imaging sequences included "cisternographic" three-dimensional T2, and delayed intravenous-enhanced three-dimensional fluid-attenuation inversion recovery (DIVE-3D-FLAIR) sequences, performed with 2350 ms (bright perilymph) and 2050 ms (bright endolymph) inversion times. The bright endolymph images were subtracted from bright perilymph images to create a composite image with bright perilymph, dark endolymph, and intermediate bone signals. MAIN OUTCOME MEASURES: MRI finding of endolymphatic hydrops. RESULTS: In all five affected ears in four patients who continued to experience severe vertigo, hydrops was found on high resolution MRI on the operated ear. The appearance on MRI was no different than in patients with endolymphatic hydrops (EH) who have not had surgery. CONCLUSIONS: The present study demonstrates the persistence of endolymphatic hydrops in patients who have failed ELS. Future studies evaluating for the presence or absence of endolymphatic hydrops in patients who claim to obtain relief from ELS.


Assuntos
Hidropisia Endolinfática/cirurgia , Anastomose Endolinfática , Falha de Tratamento , Hidropisia Endolinfática/etiologia , Hidropisia Endolinfática/patologia , Feminino , Humanos , Imageamento por Ressonância Magnética , Masculino , Doença de Meniere/complicações , Pessoa de Meia-Idade
10.
Eur Arch Otorhinolaryngol ; 272(12): 3645-50, 2015 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-25488280

RESUMO

This study aims to compare the outcomes of patients with Meniere's disease submitted to either endolymphatic mastoid shunt (ES) or tenotomy of the stapedius and tensor tympani muscles (TSTM). This is a retrospective chart review of patients treated with ES or TSTM between 2000 and 2010 and followed up for at least 12 months. The main outcomes were represented by: (1) vertigo class, hearing stage and functional level according to the American Academy of Otolaryngology-Head and Neck Surgery criteria; (2) adjustment of dizziness handicap inventory (DHI) and (3) complete and substantial vertigo control using the Kaplan-Meier survival method. Sixty-three patients met the inclusion criteria: 34 underwent ES and 29 TSTM. The baseline demographic characteristics, the hearing stage, the functional level, the DHI and hearing levels were not different between the two groups. No significant difference in vertigo class was demonstrated: 66 % of TSTM patients attained class A compared to 44 % in the ES group (p = 0.14). Kaplan-Meier survival curves specific to class A showed significant differences, favoring TSTM (log-rank test, p = 0.022). TSTM patients demonstrated significantly improved functional level (p = 0.0004) and improved DHI scores (p = 0.001). Eight ES patients (25 %) demanded a second surgical attempt compared to none in the TSTM. Aural fullness was significantly improved in TSTM group (p = 0.01), while the difference in tinnitus improvement was non-significant. Hearing preservation was significantly better in TSTM group (p = 0.001). TSTM is a safe surgical procedure, with significant vertigo control rates, and important hearing preservation rates. More patients and longer follow-up are needed to support our preliminary findings.


Assuntos
Saco Endolinfático/cirurgia , Anastomose Endolinfática , Doença de Meniere , Estapédio/cirurgia , Tenotomia , Tensor de Tímpano/cirurgia , Adulto , Pesquisa Comparativa da Efetividade , Descompressão Cirúrgica/métodos , Gerenciamento Clínico , Saco Endolinfático/patologia , Anastomose Endolinfática/efeitos adversos , Anastomose Endolinfática/métodos , Feminino , Testes Auditivos/métodos , Humanos , Estimativa de Kaplan-Meier , Masculino , Doença de Meniere/patologia , Doença de Meniere/fisiopatologia , Doença de Meniere/cirurgia , Pessoa de Meia-Idade , Avaliação de Resultados em Cuidados de Saúde , Estudos Retrospectivos , Estapédio/patologia , Tenotomia/efeitos adversos , Tenotomia/métodos , Tensor de Tímpano/patologia , Vertigem/etiologia , Vertigem/cirurgia
11.
JAMA Otolaryngol Head Neck Surg ; 140(8): 754-61, 2014 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-25057891

RESUMO

IMPORTANCE: To compare the efficacy of treatments commonly offered to patients with Ménière's disease who fail conservative medical therapy including diuretics and a sodium-restricted diet. OBJECTIVES: This study compared three second-echelon treatments: the Meniett device, endolymphatic sac decompression, and intratympanic gentamicin injections to determine their comparative effectiveness and capacity to mitigate against the necessity of a surgical labyrinthectomy. DESIGN, SETTING, AND PARTICIPANTS: Retrospective observational study at an academic tertiary care center. Patients with Ménière's disease who failed primary medical management were evaluated after treatment with a Meniett device (n=20), endolymphatic sac decompression (n=23) or intratympanic gentamicin injections (n=17). Cases were included if auditory and vertigo control data were available before and a minimum of two years after treatment, in patients without previous otologic surgery or intratympanic injections. Average age ranged from 54 to 75 years. INTERVENTIONS: Use of the Meniett device, endolymphatic sac shunt decompression surgery or intratympanic gentamicin injections using variable doses and injection schedules. MAIN OUTCOMES AND MEASURES: Proportion of patients with vertigo control and hearing preservation by a modified version of the AAO-HNS criteria after second-echelon treatment, thus not requiring definitive labyrinthectomy. RESULTS: Despite endolymphatic sac surgery demonstrating a longer duration (61 months) prior to labyrinthectomy, no differences were found between the 3 treatment options in terms of patients going on to definitive labyrinthectomy or in the number of months of symptom relief following treatment. There was also no difference in residual auditory perception across the 3 groups. CONCLUSIONS AND RELEVANCE: No significant therapeutic differences were found between the studied second-echelon treatments for symptom relief of Ménière's disease.


Assuntos
Antibacterianos/administração & dosagem , Anastomose Endolinfática/métodos , Doença de Meniere/terapia , Idoso , Descompressão Cirúrgica/instrumentação , Descompressão Cirúrgica/métodos , Dieta Hipossódica , Diuréticos/administração & dosagem , Feminino , Gentamicinas/administração & dosagem , Humanos , Injeções Intralesionais , Doença de Meniere/cirurgia , Pessoa de Meia-Idade , Retratamento , Estudos Retrospectivos , Teste do Limiar de Recepção da Fala , Falha de Tratamento , Resultado do Tratamento
12.
BMJ Case Rep ; 20122012 Oct 09.
Artigo em Inglês | MEDLINE | ID: mdl-23048004

RESUMO

In head and neck surgery, peripheral sensory nerves are at risk for traumatic injury. These injuries are known to be peripheral triggers of chronic headaches if left untreated or unrecognised. We report the case of a patient that presented with a severe headache, nausea and emesis of 2 years duration following endolymphatic shunt placement for Meniere's disease. Nerve blockade suggested a peripheral trigger, and surgical exploration of the incision site revealed traumatic neuromas of the greater auricular and lesser occipital nerves. Subsequent nerve resection yielded complete symptomatic relief. This is the first case report of a peripherally triggered migraine headache due to the development of neuromas of the greater auricular and lesser occipital nerves, also representing a previously unreported complication of endolymphatic shunt placement. It is recommended that in patients presenting with intractable migraines and a history of head and neck surgery, diagnostic nerve blockage be used to assess for neuromas.


Assuntos
Nervos Cranianos/patologia , Anastomose Endolinfática/efeitos adversos , Transtornos da Cefaleia/etiologia , Doença de Meniere/cirurgia , Transtornos de Enxaqueca/etiologia , Neuroma/complicações , Complicações Pós-Operatórias/etiologia , Nervos Cranianos/cirurgia , Feminino , Transtornos da Cefaleia/cirurgia , Humanos , Doença de Meniere/complicações , Pessoa de Meia-Idade , Transtornos de Enxaqueca/cirurgia , Náusea/etiologia , Bloqueio Nervoso , Neuroma/cirurgia , Procedimentos Neurocirúrgicos , Complicações Pós-Operatórias/cirurgia , Vômito/etiologia
13.
Otolaryngol Clin North Am ; 43(5): 1091-111, 2010 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-20713247

RESUMO

Medical treatment for Meniere's disease is effective in controlling vertigo for approximately 85% of patients. However, when disabling vertigo continues, surgical therapy is indicated. Several surgical approaches are performed to control the symptoms of peripheral vestibular disorders refractory to medical measures, each procedure having many technical variations. Surgery is usually reserved for patients with disabling vertigo. Here, the authors discuss surgical options for vertigo control in Meniere's disease and review the literature on outcomes of these management options. The authors discuss endolymphatic sac shunt (ie, endolymphatic mastoid shunt), vestibular nerve section, cochleosacculotomy, and labyrinthectomy. When looking at data based on patient ratings, the authors find that surgery improves vertigo in endolymphatic sac shunt, vestibular nerve section, and labyrinthectomy groups and improves imbalance for the endolymphatic sac shunt and vestibular nerve section groups. Labyrinthectomy and translabyrinthine vestibular nerve section both offer excellent control of intractable vertigo. However, patients undergoing translab yrinthine vestibular nerve section are more likely to show improvement in imbalance and functional disability. This outcome is more likely for diagnoses other than Meniere's disease. There are potential prognostic factors that can be helpful in the preoperative or postoperative counseling of patients undergoing surgical treatment of vertigo. Patients who rate themselves as more disabled before surgery are less likely to achieve the best outcomes. Several other factors, such as duration of disease, contralateral tinnitus, eye disease, and allergy, may play a role.


Assuntos
Doença de Meniere/cirurgia , Cóclea/cirurgia , Anastomose Endolinfática , Humanos , Procedimentos Neurocirúrgicos , Nervo Vestibular/cirurgia , Vestíbulo do Labirinto/cirurgia
14.
Otol Neurotol ; 31(4): 649-55, 2010 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-20431498

RESUMO

OBJECTIVE: To compare proportions of the combined outcome of vertigo control and hearing preservation between intratympanic gentamicin injections and endolymphatic sac shunt surgery for intractable vertigo in Ménière's disease patients. STUDY DESIGN: Analysis of published data and retrospective review. SETTING: Tertiary otologic referral center. PATIENTS: Patients with Ménière's disease who had failed medical management: 183 surgical patients (shunt group) and 203 patients obtained from 6 published gentamicin treatment studies (gentamicin group). Cases were included if hearing and vertigo data were available before and after treatment with no previous surgical or injection treatment. Average patient age ranged from 45 to 59 years across studies. Gentamicin studies had nearly equal female to male subjects, whereas the shunt group was 60% female. INTERVENTIONS: Endolymphatic sac shunt surgery or intratympanic gentamicin treatment of differing doses and injection schedules. MAIN OUTCOME MEASURE: Proportion of patients with best combined vertigo control/hearing preservation. Hearing preservation is 10 dB or less increase in pure-tone average. Outcomes were categorized as follows: complete vertigo control/hearing preservation (best), complete vertigo control/hearing loss, incomplete vertigo control/hearing preservation, and incomplete vertigo control/hearing loss (worst). RESULTS: The shunt group showed a significantly higher percentage of the best outcome (62%) than the gentamicin group (56%, p

Assuntos
Orelha Interna/cirurgia , Anastomose Endolinfática , Gentamicinas/uso terapêutico , Doença de Meniere/tratamento farmacológico , Doença de Meniere/cirurgia , Adulto , Idoso , Antibacterianos/administração & dosagem , Antibacterianos/uso terapêutico , Audiometria de Tons Puros , Distribuição de Qui-Quadrado , Feminino , Gentamicinas/administração & dosagem , Perda Auditiva/tratamento farmacológico , Perda Auditiva/cirurgia , Humanos , Injeções , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Resultado do Tratamento , Vertigem/tratamento farmacológico , Vertigem/cirurgia , Testes de Função Vestibular
15.
Eur Arch Otorhinolaryngol ; 267(1): 21-6, 2010 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-19506891

RESUMO

Endolymphatic mastoid shunt surgery (EMSS) is widely performed in patients with medically intractable Meniere's disease. Although many patients report an improvement of symptoms after surgery, the mechanisms which are responsible for the relief of complaints are not known. To date, only few studies exist which studied the influence of EMSS on vestibular function. The present study examines the effect of EMSS on saccule function by measuring vestibular evoked myogenic potentials and the effect on lateral semicircular canal function by sinusoidal harmonic acceleration (SHA) testing. No changes in vestibulo-collic reflexes were found after surgery compared to before surgery. SHA testing resulted in comparable phase lag and gain pre- and postoperatively. Although central compensation is clinically evident no effect in specific vestibular diagnostic testing is seen. Modulations of canal-otolith interaction might suggest a change of symptoms. The only method so far to evaluate the success of EMSS is the patient's subjective assessment.


Assuntos
Anastomose Endolinfática/métodos , Processo Mastoide/cirurgia , Doença de Meniere/cirurgia , Membrana dos Otólitos/cirurgia , Sáculo e Utrículo/fisiopatologia , Canais Semicirculares/fisiopatologia , Potenciais Evocados Miogênicos Vestibulares/fisiologia , Adulto , Idoso , Feminino , Seguimentos , Humanos , Masculino , Doença de Meniere/fisiopatologia , Pessoa de Meia-Idade , Membrana dos Otólitos/fisiopatologia , Estudos Retrospectivos , Sáculo e Utrículo/cirurgia , Canais Semicirculares/cirurgia , Resultado do Tratamento , Testes de Função Vestibular
16.
Otolaryngol Head Neck Surg ; 141(2): 237-42, 2009 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-19643258

RESUMO

OBJECTIVE: To evaluate changes in vertigo and hearing from patients with Ménière's disease managed by endolymphatic mastoid shunt (EMS). STUDY DESIGN: Case series with chart review. SETTING: Tertiary referral center. SUBJECTS AND METHODS: Data from 16 patients were analyzed using 1995 AAO-HNS criteria. RESULTS: Among 16 patients, six had class A vertigo control two years after treatment, five had class B, one class C, three class D, and one class F. At four years after surgery, seven patients had class A, four class B, three class C, and two class F. The mean functional level before surgery was 4.8 and improved to 2.9 and 2.6 at two years and four years after surgery, respectively. The bone conduction pure-tone averages (four frequencies) were 43.3 before surgery and improved to 33.5 dB HL and 35.5 dB HL at three and six months after surgery, respectively. At two years of follow-up, the hearing level was 38.6 dB HL and was not different from the preoperative hearing level. Two years after surgery, the hearing level gradually decreased and was 42.0 dB HL at five years of follow-up. CONCLUSION: EMS appears to be beneficial in the short term for the symptomatic patients.


Assuntos
Audiometria de Tons Puros/métodos , Anastomose Endolinfática/métodos , Audição , Processo Mastoide/cirurgia , Doença de Meniere/cirurgia , Adolescente , Adulto , Idoso , Feminino , Seguimentos , Hospitais Universitários , Humanos , Masculino , Processo Mastoide/fisiopatologia , Doença de Meniere/fisiopatologia , Pessoa de Meia-Idade , Qualidade de Vida , Estudos Retrospectivos , Percepção da Fala , Fatores de Tempo , Resultado do Tratamento , Vertigem/cirurgia
17.
Ann Otol Rhinol Laryngol ; 118(12): 852-8, 2009 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-20112519

RESUMO

OBJECTIVES: We recorded and compared the vestibular evoked myogenic potentials (VEMPs) before use of an endolymphatic mastoid shunt (EMS) and 1, 12, and 48 months after placement of the shunt. METHODS: Air-conducted VEMPs were recorded in 28 patients affected by intractable Meniere's disease and treated with placement of an EMS. RESULTS: One month and 12 months after the surgery, VEMPs were not detectable in the operated ear in 100% and 86% of the patients, respectively. Forty-eight months after the surgery, they were elicited in 79% of the patients. CONCLUSIONS: We conclude that VEMPs are a clinically useful tool in the postoperative follow-up of patients with an EMS.


Assuntos
Anastomose Endolinfática , Potenciais Evocados Auditivos/fisiologia , Potencial Evocado Motor/fisiologia , Doença de Meniere/fisiopatologia , Doença de Meniere/cirurgia , Vestíbulo do Labirinto/fisiopatologia , Adulto , Idoso , Feminino , Seguimentos , Humanos , Masculino , Processo Mastoide , Pessoa de Meia-Idade , Reflexo Acústico/fisiologia , Estudos Retrospectivos , Resultado do Tratamento , Testes de Função Vestibular
18.
Ann Otol Rhinol Laryngol ; 117(12): 871-5, 2008 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-19140530

RESUMO

OBJECTIVES: Although there exist undisputed methods to permanently silence the aberrant end organ, controversy surrounds the durable efficacy of non-ablative interventions. This study provides a contemporary review of our institution's clinical experience in performing endolymphatic mastoid shunt surgery (EMSS) in patients with medically refractory endolymphatic hydrops, or Meniere's disease. METHODS: Between 1984 and 2002, 1,612 patients were referred to our institution with a diagnosis of Meniere's disease. Of these referrals, 1,172 patients met the criteria for Meniere's disease. Although 553 patients responded to medical management, 486 patients underwent EMSS and 133 patients had refractory disease that required chemical or surgical obliterative interventions. The retrospective study utilizes data collected on 226 patients who were followed for a minimum of 5 years. RESULTS: Overall, 78% patients responded favorably to EMSS, according to the functional level scale and class categories delineated by the American Academy of Otolaryngology-Head and Neck Surgery 1995 guidelines for control of vertigo. According to the Arenberg anatomic classification for endolymphatic sac location, EMSS achieved adequate control of vertigo in 86% of type I cases, 90% of type II cases, and 82% of type III cases. CONCLUSIONS: Endolymphatic mastoid shunt surgery is a relatively safe, effective procedure for the long-term control of vertigo in patients with medically refractory Meniere's disease.


Assuntos
Anastomose Endolinfática , Doença de Meniere/cirurgia , Adolescente , Adulto , Idoso , Antibacterianos/uso terapêutico , Orelha Interna/cirurgia , Feminino , Seguimentos , Gentamicinas/uso terapêutico , Humanos , Masculino , Doença de Meniere/classificação , Pessoa de Meia-Idade , Estudos Retrospectivos , Índice de Gravidade de Doença , Membrana Timpânica , Vertigem/terapia , Nervo Vestibular/cirurgia , Adulto Jovem
19.
Otolaryngol Head Neck Surg ; 136(3): 415-21, 2007 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-17321870

RESUMO

OBJECTIVE: This study compares the efficacy of endolymphatic mastoid shunt (EMS) versus endolymphatic sac decompression (ESD) without sac incision for the treatment of Ménière's disease. STUDY DESIGN AND SETTING: The AAO-HNS Guidelines for the Diagnosis and Evaluation of Therapy in Ménière's disease were used to retrospectively identify suitable candidates for the study. All patients who failed medical management and underwent either endolymphatic-mastoid shunt (EMS) (n = 88) or endolymphatic sac decompression (ESD) (n = 108) were selected for review using the AAO-HNS guidelines. The study was carried out at a tertiary care neurotology private practice. RESULTS: EMS and ESD were equally effective in reducing the incidence and severity of vertigo attacks with significant improvement in 67 percent and 66 percent of patients, respectively. CONCLUSION: Both EMS and ESD are effective, nondestructive alternatives for patients who have failed medical management of Ménière's disease with similar long-term hearing outcomes. SIGNIFICANCE: This is the only study within the same institution using AAO-HNS guidelines comparing EMS versus ESD.


Assuntos
Descompressão Cirúrgica , Saco Endolinfático/cirurgia , Anastomose Endolinfática , Doença de Meniere/cirurgia , Atividades Cotidianas , Audiometria de Tons Puros , Seguimentos , Audição/fisiologia , Humanos , Pessoa de Meia-Idade , Reoperação , Estudos Retrospectivos , Percepção da Fala/fisiologia , Zumbido/prevenção & controle , Resultado do Tratamento , Vertigem/prevenção & controle
20.
J Vestib Res ; 17(2-3): 113-8, 2007.
Artigo em Inglês | MEDLINE | ID: mdl-18413904

RESUMO

Caloric testing in prone/supine position and constant velocity off-vertical axis rotation (OVAR) in yaw axis (rotate-then-tilt paradigm) can evaluate labyrinth function and vestibular-ocular reflex (VOR) behaviour before and after endolymphatic shunt surgery (ESS). Preoperative and postoperative otolith dysfunction can be documented by constant velocity OVAR, before the VOR is modulated by the vestibular compensation. Vestibulo-ocular responses in prone/supine position and linear VOR (lVOR) OVAR responses were observed in 10 patients before and after ESS. Ipsilateral caloric reaction in prone/supine position was reduced after ESS. Otolith-ocular function and canal-otolith-interaction were improved postoperatively. Meniere's patients with bias component opposite to normal when rotating towards the lesioned ear showed relief of symptoms postoperatively. The bias component returning to normal can help to identify the relief of Meniere's attacks after ESS. The canal-otolith interaction can be observed pre- and postoperatively by means of caloric reaction in prone/supine position as part of the clinical routine.


Assuntos
Anastomose Endolinfática , Doença de Meniere/fisiopatologia , Doença de Meniere/cirurgia , Movimentos da Cabeça , Humanos , Membrana dos Otólitos/fisiopatologia , Período Pós-Operatório , Postura , Cuidados Pré-Operatórios , Estudos Retrospectivos , Testes de Função Vestibular , Vestíbulo do Labirinto/fisiopatologia , Testes Visuais
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